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Splicing factor 1(Phospho Ser82) Polyclonal Antibody, 50ul ssDNA Synthesis This protein binds to the

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Splicing factor 1(Phospho Ser82) Polyclonal Antibody, 50ul ssDNA Synthesis This protein binds to theThis gene encodes a nuclear pre mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site together with the large subunit of U2 auxiliary factor (U2AF) and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre mRNA retention and transcriptional repression. The encoded protein contains an N terminal U2AF ligand motif a central hnRNP K homology motif

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Description

This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR

Despite its single-exon nature| this chromosome 5 locus contains an open reading frame that could putatively encode a full-length germ cell-less related protein

It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets

Assuming that human lipophilins are the functional counterparts of prostatein| they may be transcriptionally regulated by steroid hormones| with the ability to bind androgens| other steroids and possibly bind and concentrate estramustine| a chemotherapeutic agent widely used for prostate cancer

It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic

Splicing factor 1(Phospho Ser82) Polyclonal Antibody, 50ul ssDNA Synthesis This protein binds to theThis gene encodes a nuclear pre mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site together with the large subunit of U2 auxiliary factor (U2AF) and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre mRNA retention and transcriptional repression. The encoded protein contains an N terminal U2AF ligand motif a central hnRNP K homology motif

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